BESE Prof Antonio Adamo Team-41


The Stem Cell and DIsease Laboratory focuses on the use of human embryonic stem cells (hESCs) and patient-derived induced pluripotent stem cells (iPSCs) to model the onset and progression of human disorders linked to copy number variations “in a dish.” Prof. Adamo's team developed the largest cohort of Klinefelter syndrome (karyotype 47,XXY) and high-grade X aneuploid iPSCs (karyotype 48,XXXY and 49,XXXXY). We use this unique cellular model to study the molecular dysregulations associated with X chromosome aneuploidy during the earliest stages of human development.

Professor Adamo’s team combines reprogramming, organoid derivation, and genome editing techniques with a multi-omics approach to identify the transcriptional and epigenetic signatures underlying human diseases.

Latest News

16 June, 2023

The STEMD LAB got a STAR Protocols Journal cover

Our study was selected for the cover of STAR Protocols Journal - Volume 4, Number 2, June 16th, 2023 (Cell Press)

Read more

17 August, 2023


First-of-its-kind Saudi stem cell study provides insight into a genetic condition

Read more

08 November, 2019

CRG Grant Awarded to STEMD Lab

Congratulations to Professor Adamo and STEMD Lab members on the receipt of the CRG Grant

Read more