Publications after joining KAUST

 
15. Astro V. and A. Adamo*. ‘Generation of iPSC Cell Lines from Patients with Sex Chromosome Aneuploidies.’ Methods Mol Biol. 2024:2770:185-200. doi: 10.1007/978-1-0716-3698-5_14 *Corresponding author

14. Astro V., Fiacco E., K. J. Cardona-Londoño, T. Abu-Almagd, A. Kokandi, N. Alrayes, J. Alama, and A. Adamo*. ‘A transcriptomic signature of X chromosome overdosage in Saudi Klinefelter syndrome induced pluripotent stem cells.’ Endocrine Connections 2023 Apr 26;12(5):e220515. doi: 10.1530/EC-22-0515 *Corresponding author

13. V Astro, G Ramirez-Calderon, A Adamo*, Protocol to measure calcium spikes in cardiomyocytes obtained from human pluripotent stem cells using a ready-to-use media, STAR protocols 4 (2), 102252, DOI: 10.1016/j.xpro.2023.102252. *Corresponding author, Cover photo.

12. Astro V, Ramirez-Calderon G, Pennucci R, Caroli J, Saera-Vila A, Cardona-Londoño KJ, Forastieri C, Fiacco E, Ramirez-Calderon G, Maksoud F, Alowaysi M, Sogne E, Falqui A, Gonzàlez F, Montserrat N, Battaglioli E, Mattevi A, Adamo A*. Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymaticindependent mechanism iScience. 2022 Jun 23;25(7):104665. doi: 10.1016/j.isci.2022.104665 *Corresponding author

11. Astro V†, Al-Owaysi M†, Fiacco E†, Saera-Vila A, Cardona- Londoño KJ, Cigliano RA, Adamo A*. Pseudoautosomal Region 1 Overdosage Affects the Global Transcriptome in iPSCs From Patients With Klinefelter Syndrome and High-Grade X Chromosome Aneuploidies. Front. Cell Dev. Biol., 03 February 2022 https://doi.org/10.3389/fcell.2021.801597. PMID: 35186953. †equal contribution, *Corresponding author

10. Ramirez-Calderon G†, Colombo G†, Hernandez-Bautista CA, Astro V, Adamo A*: Heart in a Dish: From Traditional 2D Differentiation Protocols to Cardiac Organoids. Frontiers in Cell and Developmental Biology eCollection 2022. †equal contribution, *Corresponding author

9. Alowaysi M, Astro V, Fiacco E, Alzahrani F, Alkuraya, FS, Adamo A*: Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene. Stem Cell Research Volume 50, 2021 January. *Corresponding author

8. Fiacco E, Alowaysi M, Astro V, Adamo A*: Derivation of two naturally isogenic iPSC lines (KAUSTi006-A and KAUSTi006-B) from a mosaic Klinefelter Syndrome patient (47-XXY/46-XY). Stem Cell Research Volume 49 December 2020. *Corresponding author

7. Alowaysi M, Fiacco E, Astro V, Adamo A*: Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B). Stem Cell Research Volume 49 December 2020. *Corresponding author

6. Alowaysi M, Fiacco E, Astro V, Adamo A*: Establishment of iPSC lines from a high-grade Klinefelter Syndrome patient (49-XXXXY) and two genetically matched healthy relatives (KAUSTi003-A, KAUSTi004-A, KAUSTi004-B, KAUSTi005-A, KAUSTi005-B, KAUSTi005-C). Stem Cell Research Volume 49 December 2020. *Corresponding author

5. Fiacco E, Alowaysi M, Astro V, Adamo A*: Generation of an iPSC cohort of isogenic iPSC lines (46-XY and 47- XXY) from a non-mosaic Klinefelter Syndrome Patient (47-XXY) (KAUSTi008-A, KAUSTi008-B, KAUSTi008-C, KAUSTi008-D, KAUSTi008-E, KAUSTi008-F, KAUSTi008-G). Stem Cell Research Volume 50 2021 January. *Corresponding author

4. Alowaysi M, Astro V, Fiacco E, Adamo A*: Generation of two iPSC lines (KAUSTi001-A, KAUSTi002-A) from a rare high-grade Klinefelter Syndrome patient (49-XXXXY) carrying a balanced translocation t(4,11) (q35,q23). Stem Cell Research Volume 49 December 2020. *Corresponding author

3. Alam T, Alazmi M, Naser R, Huser F, Momin AA, Astro V, Hong S, Walkiewicz KW, Canlas CG, Huser R, Ali AJ, Merzaban J, Adamo A, Jaremko M, Jaremko Ł, Bajic VB, Gao X, Arold ST. (2019) Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs. Bioinformatics. 2019 Oct 4.

2. Astro V. Adamo A.* (2018) Epigenetic Control of Endocrine Pancreas Differentiation in vitro: Current Knowledge and Future Perspectives. Frontiers in Cell and Dev. Bio. 2018; 6: 141. * Corresponding author

1. Germain PL, Vitriolo A, Adamo A, Laise P, Das V, Testa G (2016) RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods. Nucleic Acids Res. 2016 Jun 20;44(11):5054-67

Publications before joining KAUST

7. Adamo A.†, Atashpaz S.†, Germain P.-L.†, Zanella M., D’Agostino G., Albertin V., Chenoweth J., Micale L., Fusco M., Unger C., Augello B., Palumbo O., Hamilton B., Carella M., Donti E., Pruneri G., Selicorni A., Biamino E., Prontera P., McKay R., Merla G. & Testa G. (2015) 7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages. Nat. Genetics 2015 Feb;47(2):132-41 † Equal contribution. Cover Photo.

6. Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC. (2012) Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12556-61.

5. Montserrat N, de Oñate L, Garreta E, González F, Adamo A, Eguizábal C, Häfner S, Vassena R, Izpisúa Belmonte JC. (2011) Generation of feeder free pig induced pluripotent stem cells without Pou5f1. Cell Transplant, Sep 23.

4. Adamo A, Barrero MJ, Izpisúa Belmonte JC. (2011) LSD1 and pluripotency: a new player in the network. Cell Cycle 10(19): 3215-6.

3. Adamo A, Sesé B, Boue S, Castaño J, Paramonov I, Barrero MJ, Izpisúa Belmonte JC. (2011) LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells. Nat Cell Biol 13(6): 652-60. Cover photo.

2. Zibetti C, Adamo A, Binda C, Forneris F, Toffolo E, Verpelli C, Ginelli E, Mattevi A, Sala C, Battaglioli E. (2010) Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system. J Neurosci 30(7): 2521-32.

1. Forneris F, Binda C, Adamo A, Battaglioli E, Mattevi A. (2007) Structural basis of LSD1-CoREST selectivity in histone H3 recognition. J Biol Chem 282 (28): 20070-4.