Publications at KAUST:                                                                                                                                                        

1. Veronica Astro, Kelly Yojanna Cardona-Londoño, Lorena Viridiana Cortés-Medina, Rawan Alghamdi, Gustavo Ramírez-Calderón, Fotios Kefalas, Jair Dilmé-Capó, Santiago Radío, Antonio Adamo . An iPSC-based model of 47,XYY Jacobs Syndrome reveals a DNA methylation-independent transcriptional dysregulation shared with male X aneuploid cells. Genome Res. 2025 Jul 1;35(7):1503-1517.doi: 10.1101/gr.279716.124

1. Gustavo Ramirez-Calderon, Abdulelah Saleh, Tania Cecilia Hidalgo Castillo, Victor Druet, Bayan Almarhoon, Latifah Almulla, Antonio Adamo, Sahika Inal Enhancing the maturation of human pluripotent stem cell-derived cardiomyocytes with an n-type organic semiconductor coating. ACS Applied Materials & Interfaces.ACS Appl Mater Interfaces. 2024 Dec 11;16(49):66900-66910. doi: 10.1021/acsami.3c18919. Epub 2024 Apr 15.

    

2. Veronica Astro, Antonio Adamo^. Generation of iPSC Cell Lines from Patients with Sex Chromosome Aneuploidies. Methods Mol Biol. 2024:2770:185-200. doi: 10.1007/978-1-0716-3698-5_14.

    

3. Veronica Astro, Gustavo Ramirez-Calderon, Antonio Adamo. Protocol to measure calcium spikes in cardiomyocytes obtained from human pluripotent stem cells using a ready-to-use media.STAR Protoc. 2023 Apr 13;4(2):102252. doi: 10.1016/j.xpro.2023.102252.

    

4. Veronica Astro, Elisabetta Fiacco, Kelly Johanna Cardona-Londoño, Ilario De Toma, Hams Saeed Alzahrani, Jumana Alama, Amal Kokandi, Taha Abo-Almagd Abdel-Meguid Hamoda, Majed Felemban, Antonio Adamo . A transcriptomic signature of X chromosome overdosage in Saudi Klinefelter syndrome induced pluripotent stem cells. Endocr Connect. 2023 Apr 26;12(5):e220515. doi: 10.1530/EC-22-0515.

    

5. Veronica Astro, Gustavo Ramirez-Calderon, Roberta Pennucci, Jonatan Caroli, Alfonso Saera-Vila, Kelly Cardona-Londoño, Chiara Forastieri, Elisabetta Fiacco, Fatima Maksoud, Maryam Alowaysi, Elisa Sogne , Andrea Falqui, Federico Gonzàlez, Nuria Montserrat, Elena Battaglioli, Andrea Mattevi , Antonio Adamo. Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism. iScience. 2022 Jun 23;25(7):104665. doi: 10.1016/j.isci.2022.104665. eCollection 2022 Jul 15.

    

6. Gustavo Ramirez-Calderon , Giovanni Colombo , Carlos A Hernandez-Bautista , Veronica Astro, Antonio Adamo. Heart in a Dish: From Traditional 2D Differentiation Protocols to Cardiac Organoids. Front Cell Dev Biol. 2022 Feb 17:10:855966. doi: 10.3389/fcell.2022.855966. eCollection 2022.

    

7. Veronica Astro, Maryam Alowaysi, Elisabetta Fiacco, Alfonso Saera-Vila, Kelly J Cardona-Londoño, Riccardo Aiese Cigliano , Antonio Adamo. Pseudoautosomal Region 1 Overdosage Affects the Global Transcriptome in iPSCs From Patients With Klinefelter Syndrome and High-Grade X Chromosome Aneuploidies. Front Cell Dev Biol. 2022 Feb 3:9:801597. doi: 10.3389/fcell.2021.801597. eCollection 2021.

    

8. Maryam Alowaysi, Veronica Astro, Elisabetta Fiacco, Fatema Alzahrani, Fowzan S Alkuraya, Antonio Adamo. Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene. Stem Cell Res. 2021 Jan:50:102148. doi: 10.1016/j.scr.2020.102148. Epub 2020 Dec 28.

    

9. Elisabetta Fiacco, Maryam Alowaysi, Veronica Astro, Antonio Adamo. Generation of an iPSC cohort of isogenic iPSC lines (46-XY and 47-XXY) from a non-mosaic Klinefelter Syndrome patient (47-XXY) (KAUSTi008-A, KAUSTi008-B, KAUSTi008-C, KAUSTi008-D, KAUSTi008-E, KAUSTi008-F, KAUSTi008-G). Stem Cell Res. 2021 Jan:50:102119. doi: 10.1016/j.scr.2020.102119. Epub 2020 Dec 10.

    

10. Maryam Alowaysi, Elisabetta Fiacco, Veronica Astro, Antonio Adamo .Generation of two iPSC lines (KAUSTi001-A, KAUSTi002-A) from a rare high-grade Klinefelter Syndrome patient (49-XXXXY) carrying a balanced translocation t(4,11) (q35,q23). Stem Cell Res. 2020 Dec:49:102098. doi: 10.1016/j.scr.2020.102098. Epub 2020 Nov 24.

     

11. Elisabetta Fiacco, Maryam Alowaysi, Veronica Astro, Antonio Adamo. Derivation of two naturally isogenic iPSC lines (KAUSTi006-A and KAUSTi006-B) from a mosaic Klinefelter Syndrome patient (47-XXY/46-XY). Stem Cell Res. 2020 Dec:49:102049. doi: 10.1016/j.scr.2020.102049. Epub 2020 Oct 15.

     

12. Maryam Alowaysi, Elisabetta Fiacco, Veronica Astro, Antonio Adamo. Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B).Stem Cell Res. 2020 Dec;49:102042. doi: 10.1016/j.scr.2020.102042. Epub 2020 Oct 10.

     

13. Maryam Alowaysi, Elisabetta Fiacco, Veronica Astro, Antonio Adamo . Establishment of iPSC lines from a high-grade Klinefelter Syndrome patient (49-XXXXY) and two genetically matched healthy relatives (KAUSTi003-A, KAUSTi004-A, KAUSTi004-B, KAUSTi005-A, KAUSTi005-B, KAUSTi005-C). Stem Cell Res. 2020 Dec:49:102008. doi: 10.1016/j.scr.2020.102008. Epub 2020 Sep 22.
14. Daniel Lane, Wolfgang Bermel, Paris Ning, Tae-Yong Jeong, Richard Martin, Ronald Soong, Bing Wu, Maryam Tabatabaei-Anaraki, Hermann Heumann, Marcel Gundy, Holger Boenisch, Antonio Adamo, George Arhonditsis, André J Simpson. Targeting the Lowest Concentration of a Toxin That Induces a Detectable Metabolic Response in Living Organisms: Time-Resolved In Vivo 2D NMR during a Concentration Ramp. Anal Chem. 2020 Jul 21;92(14):9856-9865. doi: 10.1021/acs.analchem.0c01370. Epub 2020 Jul 2.

     

15. Tanvir Alam, Meshari Alazmi, Rayan Naser, Franceline Huser, Afaque A Momin, Veronica Astro, SeungBeom Hong, Katarzyna W Walkiewicz, Christian G Canlas, Raphaël Huser, Amal J Ali, Jasmeen Merzaban, Antonio Adamo, Mariusz Jaremko, Łukasz Jaremko, Vladimir B Bajic, Xin Gao, Stefan T Arold. Proteome-level assessment of origin, prevalence and function of leucine-aspartic acid (LD) motifs. Bioinformatics. 2020 Feb 15;36(4):1121-1128. doi: 10.1093/bioinformatics/btz703.

     

16. Veronica Astro, Antonio Adamo. Epigenetic Control of Endocrine Pancreas Differentiation in vitro: Current Knowledge and Future Perspectives. Review Front Cell Dev Biol. 2018 Oct 25:6:141. doi: 10.3389/fcell.2018.00141. eCollection 2018.

     

17. Pierre-Luc Germain, Alessandro Vitriolo, Antonio Adamo, Pasquale Laise, Vivek Das, Giuseppe Testa. RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods. Nucleic Acids Res. 2016 Jun 20;44(11):5054-67. doi: 10.1093/nar/gkw448. Epub 2016 May 17.

     

18. Liora Bliumkin, Rudraksha Dutta Majumdar, Ronald Soong, Antonio Adamo, Jonathan P D Abbatt, Ran Zhao, Eric Reiner, André J Simpson. Development of an in Situ NMR Photoreactor To Study Environmental Photochemistry. Environ Sci Technol. 2016 Jun 7;50(11):5506-16. doi: 10.1021/acs.est.6b00361. Epub 2016 May

     

19. Daria Bunina, Pierre-Luc Germain, Alejandro Lopez Tobon, Nadine Fernandez-Novel Marx, Christian Arnold, Andrew Ahern, Annique Claringbould, Mang,Ching Lai, Sampath Rangasamy, Vinodh Narayanan, Peter Lorentzen, Karen, M. Park, Antonio Adamo, Giuseppe Testa, Judith Zaugg, Kyung-Min Noh. Pathological LSD1 mutations repress enhancer-mediated gene regulatory networks in early differentiation. BioRxiv. September 22, 2021. doi: https://doi.org/10.1101/2021.08.11.455900.

     

20. Tanvir Alam, Meshari Alazmi, Rayan Naser, Franceline Huser, Afaque A Momin, Veronica Astro, SeungBeom Hong, Katarzyna W Walkiewicz, Christian G Canlas, Raphaël Huser, Amal J Ali, Jasmeen Merzaban, Antonio Adamo, Mariusz Jaremko, Łukasz Jaremko, Vladimir B Bajic, Xin Gao, Stefan T Arold. Proteome-level assessment of origin, prevalence and function of leucine-aspartic acid (LD) motifs. Bioinformatics. 2020 Feb 15;36(4):1121-1128. doi: 10.1093/bioinformatics/btz703.

     

    Publications before joining KAUST                                                                                                                              

     

21. Antonio Adamo, Sina Atashpaz, Pierre-Luc Germain, Matteo Zanella, Giuseppe D'Agostino, Veronica Albertin, Josh Chenoweth, Lucia Micale, Carmela Fusco, Christian Unger, Bartolomeo Augello, Orazio Palumbo, Brad Hamilton, Massimo Carella, Emilio Donti, Giancarlo Pruneri, Angelo Selicorni, Elisa Biamino, Paolo Prontera, Ronald McKay, Giuseppe Merla, Giuseppe Testa. 7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages. Nat Genet. 2015 Feb;47(2):132-41. doi: 10.1038/ng.3169. Epub 2014 Dec 15.

     

22. Alessandra Giorgetti 1, Maria C N Marchetto, Mo Li, Diana Yu, Raffaella Fazzina, Yangling Mu, Antonio Adamo, Ida Paramonov, Julio Castaño Cardoso, Montserrat Barragan Monasterio, Cedric Bardy, Riccardo Cassiani-Ingoni, Guang-Hui Liu, Fred H Gage, Juan Carlos Izpisua BelmonteCord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. . Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12556-61. doi: 10.1073/pnas.1209523109. Epub 2012 Jul 18.

     

23. Nuria Montserrat 1, Lorena de Oñate, Elena Garreta, Federico González, Antonio Adamo, Cristina Eguizábal, Sophia Häfner, Rita Vassena, Juan Carlos Izpisua Belmonte. Generation of feeder-free pig induced pluripotent stem cells without Pou5f1. Cell Transplant. 2012;21(5):815-25. doi: 10.3727/096368911X601019. Epub 2011 Sep 23.

     

24. Antonio Adamo, Maria J Barrero, Juan Carlos Izpisua Belmonte. LSD1 and pluripotency: a new player in the network. Cell Cycle. 2011 Oct 1;10(19):3215-6. doi: 10.4161/cc.10.19.17052. Epub 2011 Oct 1.

     

25. Antonio Adamo , Borja Sesé, Stephanie Boue, Julio Castaño, Ida Paramonov, Maria J Barrero, Juan Carlos Izpisua Belmonte. LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells. Nat Cell Biol. 2011 Jun;13(6):652-9. doi: 10.1038/ncb2246. Epub 2011 May 22.Cover picture.

     

26. Cristina Zibetti , Antonio Adamo, Claudia Binda, Federico Forneris, Emanuela Toffolo, Chiara Verpelli, Enrico Ginelli, Andrea Mattevi, Carlo Sala, Elena Battaglioli. Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system. J Neurosci. 2010 Feb 17;30(7):2521-32. doi: 10.1523/JNEUROSCI.5500-09.2010.

     

27. Federico Forneris ¹, Claudia Binda, Antonio Adamo, Elena Battaglioli, Andrea Mattevi. Structural basis of LSD1-CoREST selectivity in histone H3 recognition. J Biol Chem. 2007 Jul 13;282(28):20070-4. doi: 10.1074/jbc.C700100200. Epub 2007 May 30.