Siyi FU

Research Staff

Post Doc.

Current

Location:

2304-WS25

Research Interests

Stem Cell Biology, Embryology and Developmental Biology.

• Human embryonic stem cells and human adult stem cells culture and differentiation.

• Molecular cloning, histological analysis, spatial fluorescent imaging and sc-sequencing.

• Mice embryo retrieval, micro-injection, embryo culture, staining and implantation.

• Mice maintenance, strain breeding, animal model establishment.

Selected Publications

Fu, Siyi*, Cheung Kwan Yeung, Ren-He Xu. Pluripotent stem cell-derived MSCs for
therapeutic applications, developmental study, and cancer research. Current Opinion in

Genetics & Development (2025). (Under review)

Fu, Siyi*, Borong Huang*, Enqin Li, Xiaoling Xu, Ren-He Xu. Chimerization of human ESCderived extraembryonic cells with the mouse blastocyst. International Journal of

Biological Sciences 2024; 20(13): 5056-5069.

Huang, Borong*, Siyi Fu*, Yanan Hao*, Xin Zhang, Cheung Kwan Yeung, Enqin Li, Xiaoling
Xu, Ningyi Shao, Ren-He Xu. Developmental potency of human ES cell-derived
mesenchymal stem cells revealed in mouse embryos following blastocyst injection.

Cell Reports 42,12 (2023): 113459. (Co-first author)

Ng, Hoi Man *, Chon Lok Lei*, Siyi Fu*, Enqin Li, Sek In Leong, Chu Iong Nip, Nga Man
Choi, Kai Seng Lai, Xi Jun Tang, Chon Lok Lei, Ren-He Xu. Heterologous vaccination
with inactivated vaccine and mRNA vaccine augments antibodies against both spike
and nucleocapsid proteins of SARS-CoV-2: a local study in Macao. Frontiers in

Immunology, Vaccines and Molecular Therapeutics. (2023):1131985. (Co-first author)

Park, Jung Woo, Siyi Fu, Borong Huang, and Ren‐He Xu. "Alternative Splicing in

Mesenchymal Stem Cell Differentiation." Stem Cells 38, no. 10 (2020): 1229-40.

Fu, Siyi, Qiying Dai, Yihua Bei, Yongqin Li, and Junjie Xiao. Chapter 7: "Exercise-Based
Cardiovascular Therapeutics: From Cellular to Molecular Mechanisms." In Lifestyle in
Heart Health and Disease, 87-97: Elsevier, 2018. 1st Edition. UK: Academic
Press.ISBN: 978-0-12-811279-3.

 

Fu, Siyi. Chapter 3: " The relationship between Telocytes and other cells." In Telocytes, 2017.

Beijing: Science Press.ISBN: 978-7-03-050003-8. (in Chinese)

Fu, Siyi, Hui Zhu, Siyi Li, Yalong Wang, Yihua Bei, and Junjie Xiao. "Telocytes in Cardiac

Protection." Current stem cell research & therapy 11, no. 5 (2016): 390-94.

Fu, Siyi, Fei Wang, Yan Cao, Qi Huang, Junjie Xiao, Changqing Yang, and Laurentiu M
Popescu. "Telocytes in Human Liver Fibrosis." Journal of cellular and molecular

medicine 19, no. 3 (2015): 676-83.

Fu, Siyi, Leqi Huang, Yalong Wang, Xing Li, Jie Li, and Junjie Xiao. "Microrna as a Novel

Player in Atrial Fibrillation." Frontiers in genetics 5 (2014): 97.

Fu, Siyi, Ran Zhuo, Mengchao Yao, Jiawen Zhang, Hanling Zhou, and Junjie Xiao. "Microrna

Basis of Physiological Hypertrophy." Frontiers in genetics 4 (2013): 253.

Bei, Yihua*, Qiulian Zhou*, Siyi Fu*, Dongchao Lv, Ping Chen, Yuanyuan Chen, Fei Wang,
and Junjie Xiao. "Cardiac Telocytes and Fibroblasts in Primary Culture: Different

Morphologies and Immunophenotypes." PLoS One 10, no. 2 (2015): e0115991. (Cofirst author)

Bei, Yihua, Siyi Fu, Xiangming Chen, Mei Chen, Qiulian Zhou, Pujiao Yu, Jianhua Yao, et al.
"Cardiac Cell Proliferation Is Not Necessary for Exercise‐Induced Cardiac Growth but
Required for Its Protection against Ischaemia/Reperfusion Injury." Journal of cellular

and molecular medicine 21, no. 8 (2017): 1648-55.

Zhuo, Ran, Siyi Fu, Shiyi Li, Mengchao Yao, Dongchao Lv, Tianzhao Xu, and Yihua Bei.
"Desregulated Micrornas in Aging-Related Heart Failure." Frontiers in genetics 5
(2014): 186.

 

Tao, Lichan, Sutong Shen, Siyi Fu, Hongyi Fang, Xiuzhi Wang, Saumya Das, Joost PG Sluijter,
et al. "Traditional Chinese Medication Qiliqiangxin Attenuates Cardiac Remodeling

after Acute Myocardial Infarction in Mice." Scientific reports 5 (2015): 8374.

Zhou, Qiulian, Lei Wei, Chongjun Zhong, Siyi Fu, Yihua Bei, Radu‐Ionuț Huică, Fei Wang,
and Junjie Xiao. "Cardiac Telocytes Are Double Positive for Cd 34/Pdgfr‐Α." Journal

of cellular and molecular medicine 19, no. 8 (2015): 2036-42.

Tao, Lichan, Yihua Bei, Ping Chen, Zhiyong Lei, Siyi Fu, Haifeng Zhang, Jiahong Xu, et al.
"Crucial Role of Mir-433 in Regulating Cardiac Fibrosis." Theranostics 6, no. 12

(2016): 2068.

Xiao, Junjie, Dongchao Lv, Jinzhe Zhou, Yihua Bei, Ting Chen, Muren Hu, Qiulian Zhou, Siyi
Fu, and Qi Huang. "Therapeutic Inhibition of Mir-4260 Suppresses Colorectal Cancer

Via Targeting Mcc and Smad4." Theranostics 7, no. 7 (2017): 1901.

Zhou, Qiulian, Dongchao Lv, Ping Chen, Tianzhao Xu, Siyi Fu, Jin Li, and Yihua Bei.
"Micrornas in Diabetic Cardiomyopathy and Clinical Perspectives." Frontiers in

genetics 5 (2014): 185.

Xiao, Junjie, Ping Chen, Yi Qu, Pujiao Yu, Jianhua Yao, Hongbao Wang, Siyi Fu, et al.
"Telocytes in Exercise‐Induced Cardiac Growth." Journal of cellular and molecular
medicine 20, no. 5 (2016): 973-79.

Education

Doctor of Philosophy, University of Macau, Taipa, Macau 2018-08 – 2022-07 Major: Biomedical sciences

Master of Science, Shanghai University, Shanghai, China 2015-09 – 2018-06 Major: Cell biology

Bachelor of Engineering, Shanghai University, Shanghai, China 2011-09 – 2015-06 Major: Bioengineering GPA: 3.60 /4.00

Professional Profile

Research Assistant 2022-09 – 2024-09 Faculty of Health Sciences, University of Macau, Taipa, Macau

Awards

  • 2024 Best Poster, 8th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows, and Research Assistants, Faculty of Health Sciences, University of Macau
  • 2018-2022 The UM Macao PhD Scholarship (MPDS), University of Macau
  • 2017-2018 National first-class scholarship, Ministry of Education of China 2016-2017 National first-class scholarship, Ministry of Education of China
  • 2015-2016 National first-class scholarship, Ministry of Education of China
  • 2015 The national second prize in the 14th “Challenge Cup” national college students’ extracurricular academic science and technology contest, the Central Communist Youth League & the China Association for Science and Technology & Ministry of Education & the Students and Scholars Association & the Guangdong Provincial Government 2015 Shanghai Outstanding Graduates, the Ministry of Education of Shanghai
  • 2015 Excellent Graduate Design (thesis), Shanghai University
  • 2014 Baosteel scholarship, Baosteel Education Foundation & Shanghai University
  • 2013-2014 The school second-class scholarship, Shanghai University
  • 2013-2014 Academic innovation scholarship, Shanghai University
  • 2012-2013 The school first-class scholarship, Shanghai University
  • 2012-2013 Academic innovation scholarship, Shanghai University
  • 2011-2012 The school second-class scholarship, Shanghai University
  • 2011 The second prize in “Newborn Cup” Billiard Sports match, Shanghai University
  • 2011 Student Pacemaker, Shanghai University

Non-KAUST Affiliations

2020-2021 Organizer & MC, FHS Postdoc/Student Seminar, Faculty of Health Sciences,
University of Macau
2020 Chair & MC, 4th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows,
and Research Assistants, Faculty of Health Sciences, University of Macau
2019-2020 Teaching Assistant, Genetics, Genomics and Bioinformatics Lab (HSCI3005),
Faculty of Health Sciences, University of Macau
2019 Booklet designer & Photographer, 3rd Symposium on Biomedical Sciences for Students,
Postdoctoral Fellows, and Research Assistants, Faculty of Health Sciences, University of
Macau
2018-2019 Teaching Assistant, Stem Cell Biology and Regenerative Medicine (HSCI4002),
Faculty of Health Sciences, University of Macau