My research interests in the STEMD lab focuses on combining CRISPR-based genetic editing tools and iPSC technique together with NGS and bioinformatics method to investigate mechanisms of genetic diseases (e.g.X chromosome aneuploidies in Klinefelter Syndrome), especially by conducting CRISPR screening in multiple iPSC- derived cell types from patients and identifying potential factors involved in disease regulation.  

Yi, H., Li, G., Long, Y., Liang, W., Cui, H., Zhang, B., Tan, Y., Li, Y., Shen, L., Deng, D., Tang, Y., Mao, C., Tian, S., Cai, Y., Zhu, Q., Hu, Y., Chen, W., & Fang, L. (2020). Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT. Oncogene, 39(28), 5152–5164.

https://doi.org/10.1038/s41388-020-1351-z *Co-authors

• 2022.09-present. Master student, Bioscience, BESE, King Abdullah University of Science and Technology (KAUST), Saudi Arabia
• 2020.07 Bachelor of Science, Biological Science Department of Biology, Southern University of Science and Technology (SUSTech), China

2021.05-2022.08 Research Assistant, School of Medicine, SUSTech, China

Biological and Environmental Science and Engineering Division (BESE)