Lubna Amir Patel

Past Members

Lab technician

Past Members

Social Profile:

Selected Publications

1.
Patel, L., Ailloud, F., Suerbaum, S., & Josenhans, C. (2024). Single-base resolution quantitative genome methylation analysis in the model bacterium Helicobacter pylori by enzymatic methyl sequencing (EM-Seq) reveals influence of strain, growth phase, and methyl homeostasis. BMC biology, 22(1), 125.
2.
Suerbaum, S., Coombs, N., Patel, L., Pscheniza, D., Rox, K., Falk, C., ... & Josenhans, C. (2022). Identification of antimotilins, novel inhibitors of Helicobacter pylori flagellar motility that inhibit stomach colonization in a mouse model. Mbio, 13(2), e03755-21.
3.
Schmitt, S., Tahk, S., Lohner, A.,... Patel L... & Subklewe, M. (2020). Fusion of bacterial flagellin to a dendritic cell-targeting αCD40 antibody construct coupled with viral or leukemia-specific antigens enhances dendritic cell maturation and activates peptide-responsive T cells. Frontiers in Immunology

Education

05/2020 – 08/2024 Max von Pettenkofer-Institut der LMU (medical microbiology), WG Prof. Christine Josenhans | Munich, Germany
Dr. rer. nat. (Awaiting evaluation by examination committee)
10/2017 – 11/2019 Ludwig-Maximilians-University Munich (LMU) | Munich, Germany
M.Sc. Biology, final grade: 1.34
08/2012 – 01/2017 Thadomal Shahani Engineering College (TSEC) | Mumbai University, India
B. Tech Biotechnology, CGPA: 8.96
08/2010 – 08/2012 St. Mira’s College | Pune University, India
Higher Secondary Certificate Exam (10+2), percentage: 93.4

Professional Profile

05/2020 – 08/2024 Doctoral thesis | Max von Pettenkofer-Institut der LMU (medical microbiology) | Munich, Germany (Supervisor: Prof. Dr. Christine Josenhans)
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Identified novel anti-virulence strategies against gastric pathogen, Helicobacter pylori by HTS
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Performed pre-clinical experiments on patented compounds
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Analysed whole genome DNA methylation in H. pylori by Illumina and Oxford Nanopore Sequencing Technology
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Expressed and purified proteins, performed SDS-PAGE, EMSA, TSA
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Executed cell-culture, ELISA, immunostaining, live cell microscopy
03/2019 – 09/2019 Master thesis | Ludwig-Maximilians-University Munich (LMU) | Munich, Germany (Supervisor: Prof. Dr. Kai Papenfort)
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Functionally characterized a dual-function sRNA in Vibrio cholerae
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Performed RNA isolation, RT-qPCR, Northern Blot, Western Blot, transcriptome (RNAseq) analysis
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Visualised protein co-localisation by fluorescence microscopy
10/2018 – 02/2019 Research Intern | Ludwig-Maximilians-University Munich (LMU) | Munich, Germany (Supervisor: Prof. Dr. Kai Papenfort)
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Mastered aseptic handling of Biosafety Level-2 organism, Vibrio cholerae
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Performed DNA and RNA isolation, molecular cloning, and immunoprecipitation experiments
01/2018 – 05/2018 Research Intern | Ludwig-Maximilians-University Munich (LMU) | Munich, Germany (Supervisor: Prof. Dr. Michael Boshart)