PhD Students
Ph.D Student
Current
Bldg. 2, Level 3. 3204 - WS 27
I joined the STEMD laboratory in 2021 as a Ph.D. student, my work consists mainly in to provide support to different projects in the lab by performing bioinformatic analysis from the experiments that my colleagues performed in the wet lab. Previously, during my master's program I gain experience performing transcriptomics analysis, my thesis studied the dysregulation of genes associated with inflammatory processes in Alzheimer's disease. I also have experience conducting research in electrophysiology and signal processing and 4 years of experience teaching at different universities in my home country.
I am interested in research combining bioinformatics, structural biology, and computational methods to address fundamental questions in Biomedical sciences.
My research project is dedicated to elucidating the impact of sex chromosome aneuploidies on transcription and regulatory mechanisms such as alternative splicing and methylation in pluripotency and during differentiation; based on an integrative approach that combines data from bulk and single-cell transcriptomics, bisulfite sequencing and structural biology.
Astro V, Ramirez-Calderon G, Pennucci R, Caroli J, Saera-Vila A, Cardona-Londoño K, Forastieri C, Fiacco E, Maksoud F, Alowaysi M, Sogne E, Falqui A, Gonzàlez F, Montserrat N, Battaglioli E, Mattevi A, Adamo A. Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism. iScience. 2022 Jun 23;25(7):104665. PMID: 35856020; PMCID: PMC9287196.
Astro V*, Alowaysi M*, Fiacco E*, Saera-Vila A, Cardona-Londoño KJ, Aiese Cigliano R, Adamo A. Pseudoautosomal Region 1 Overdosage Affects the Global Transcriptome in iPSCs From Patients With Klinefelter Syndrome and High-Grade X Chromosome Aneuploidies. Front Cell Dev Biol. 2022 Feb 3;9:801597. PMID: 35186953; PMCID: PMC8850648.
Cardona, K., Medina, J., Orrego-Cardozo, M., de Mejía, F. R., Elcoroaristizabal, X., & Galvis, C. A. N. (2021). Inflammatory gene expression profiling in peripheral blood from patients with Alzheimer’s disease reveals key pathways and hub genes with potential diagnostic utility: a preliminary study. PeerJ, 9, e12016.
Medico Salsench, E., Maroofian, R., Deng, R., Lanko, K., Nikoncuk, A., Pérez, B., ... Cardona-Londoño, K. J ., …& Barakat, T. S. (2021). Expanding the mutational landscape and clinical phenotype of the YIF1B related brain disorder. Brain, 144(10), e85-e85.
Weerts, M. J., Lanko, K., Guzmán-Vega, F. J., Jackson, A., Ramakrishnan, R., Cardona-Londoño, K. J., ... & Genomics England Research Consortium. (2021). Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome. Genetics in Medicine, 23(11), 2122-2137.
2018/02 – 2020/03: Adjunct Professor. Universidad Nacional de Colombia – Manizales Campus. Manizales, Colombia.
2018: Adjunct Professor. Universidad Católica de Manizales. Manizales, Colombia.
2016- 2020: Researcher & Lecturer. Universidad Autónoma de Manizales. Manizales, Colombia.
2014-2015: Young Researcher Fellow. Universidad Autónoma de Manizales. Manizales, Colombia.
2021. KAUST Scholarship to pursue Ph.D. Degree. King Abdullah University of Science and Technology. Thuwal, Saudi Arabia.
2018. Outstanding Master’s Thesis Distinction. Universidad Autónoma de Manizales. Manizales - Colombia.
2015. Innovative Talent Scholarship to pursue MS Degree. Colombian Center of Bioinformatics and Computational Biology. Manizales - Colombia.
2015. COLCIENCIAS Young Researcher Fellow – Administrative Department of Science, Technology, and Innovation of Colombia. Bogotá – Colombia.
2013 Honorable Mention for Academic Excellence – Universidad Autónoma de Manizales. Manizales - Colombia
2009 Bachelor Excellence Scholarship to pursue BS Degree. Universidad Autónoma de Manizales. Manizales – Colombia.
Biological and Environmental Science and Engineering Division (BESE)
Computational Bioscience Research Center (CBRC)